Organic Letters p. 3934 - 3937 (2013)
Update date:2022-08-04
Topics:
Salon, Jozef
Gan, Jianhua
Abdur, Rob
Liu, Hehua
Huang, Zhen
6-Se-guanosine phosphoramidite and RNAs have been synthesized by selenium substitution of the 6-oxygen atom, and it is revealed that the Se-derivatization is relatively stable and that bulge and wobble structures can better accommodate a large Se atom than a duplex. This Se-modification is useful in the structural study of RNAs and their protein complexes.
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Doi:10.3987/COM-12-S(N)79
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(2013)
