Asymmetric synthesis of 2,3-dihydroquinolin-4-one derivatives catalyzed by a chiral bisguanidium salt

Article abstract of DOI:10.1002/chem.201203216

Worth its salt: An orgnaocatalytic asymmetric intramolecular aza-Michael reaction and one-pot bromination reaction of activated α,β- unsaturated ketones have been realized using a chiral bisguanidium salt (see scheme). Optically enriched 2-aryl- and 2-alk