Syntheses of sialic acid isomers with inhibitory activity against neuroaminidase

DOI: 10.1016/0040-4039(92)89033-9

Source and publish data:

Tetrahedron Letters p. 5791 - 5794 (1992)

Update date:2022-08-03

Topics:

Authors:

Yamamoto

Kumazawa

Inami Inami

Teshima Teshima

Shiba Shiba

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Article abstract of DOI:10.1016/0040-4039(92)89033-9

The isomers of sialic acid (N-acetylneuroaminic acid) with 6-acetylamino group, 1a and 1b were synthesized through aldol condensation of D-glucose with oxalacetic acid. These compounds inhibit neuraminidases of influenza virus A, A₂ and B remar

Full text of DOI:10.1016/0040-4039(92)89033-9

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