New chiral auxiliaries based on conformation control, a C2-symmetric 2,2-dimethylimidazolidine and 4-chiral 2,2-dialkyloxazolidines. Synthesis and conformational analysis of acrylamide derivatives

Article abstract of DOI:10.1016/S0040-4020(01)89439-4

New chirality-controlling auxiliaries, a C₂-symmetric 2,2-dimethylimidazolidine and 4-chiral 2,2-dialkyloxazolidines, are readily prepared from a C₂-symmetric 1,2-ethanediamine and naturally occurring α-amino acids, respectively. Con