Cyclization reactions of β,β-difluoroalkyl radicals (-CF2-C·) for synthesizing gem-difluorocyclic compounds

Article abstract of DOI:10.1016/S0040-4020(01)81990-6

Cyclization reactions of β,β-difluoroalkyl radicals were carried out. 5 or 6-Exo selective radical cyclizations gave gem-difluorocyclopentane or -cyclohexane derivatives in 53-96% yields. 2,5-Disubstituted-3,3-difluorotetrahydropyran derivatives were prep