A nitrile approach to the synthesis of the side chain of vitamin D metabolites and analogues

DOI: 10.1016/S0040-4039(00)61019-5

Source and publish data:

Tetrahedron Letters p. 6683 - 6686 (1992)

Update date:2022-08-03

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Authors:

Fall Fall

Torneiro

Castedo Castedo

Mourino Mourino

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Article abstract of DOI:10.1016/S0040-4039(00)61019-5

An efficient new method for the construction of vitamin D hydroxylated side chains is described which is based on the alkylation and opening of epoxides by the α-anions derived from nitriles 6 and 7.

Full text of DOI:10.1016/S0040-4039(00)61019-5

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