European Journal of Medicinal Chemistry p. 545 - 549 (1992)
Update date:2022-08-05
Topics:
Corsano, S
Strappaghetti, G
Codagnone, A
Scapicchi, R
Marucci, G
The synthesis of a series of piperazinyl-pyridazinones is reported. The blocking activity of these compounds was determined on the pre- and postsynaptic α-adrenoreceptors of isolated rat vas deferens. For compounds 7, 17 and 18, the hypotensive activity w
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