Synthesis and pharmacological activity of some new pyridazinones

DOI: 10.1016/0223-5234(92)90189-8

Source and publish data:

European Journal of Medicinal Chemistry p. 545 - 549 (1992)

Update date:2022-08-05

Topics:

Authors:

Corsano, S

Strappaghetti, G

Codagnone, A

Scapicchi, R

Marucci, G

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Article abstract of DOI:10.1016/0223-5234(92)90189-8

The synthesis of a series of piperazinyl-pyridazinones is reported. The blocking activity of these compounds was determined on the pre- and postsynaptic α-adrenoreceptors of isolated rat vas deferens. For compounds 7, 17 and 18, the hypotensive activity w

Full text of DOI:10.1016/0223-5234(92)90189-8

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