Calcium entry blockers and activators: Conformational and structural determinants of dihydropyrimidine calcium channel modulators

DOI: 10.1021/jm00001a017

Source and publish data:

Journal of Medicinal Chemistry p. 119 - 129 (1995)

Update date:2022-08-05

Topics:

Authors:

Rovnyak Rovnyak

Kimball Kimball

Beyer Beyer

Cucinotta

DiMarco DiMarco

Gougoutas

Hedberg Hedberg

Malley Malley

McCarthy

Zhang Zhang

Moreland

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00001a017

Dihydropyrimidines 4, 6, and 15, uniquely designed to unambiguously establish structural and conformational determinants for DHP receptor occupation and for modulation of calcium channel function, were prepared and examined for calcium channel modulation.

Full text of DOI:10.1021/jm00001a017

Products guided by the article

Product name:2-<<3-nitro-2-<<5-<(tert-butyldimethylsilyl)oxy>pentyl>thio>phenyl>methylene>-3-oxobutanoic acid, 2-(trimethylsilyl)ethyl ester

Cas No:145457-73-4

R&D Labs maybe for 145457-73-4

Jiangsu Cale New Material Co.ltd

Contact:+86-515-88334667/88203550

Address:Zhongshan 3rd Road, Coastal Chemical Industry Park, Yancheng, Jiangsu, China
Taixing Shenfeng Chemical Co., Ltd.

Contact:+86-523-87117033, 87117666

Address:4# Yinsanlu, Huangqiao town, Taixing, Jiangsu, China.
Hangzhou Showland Technology Co., Ltd.

Contact:86-571-88920516

Address:ROOM2118,NO.553,WENSAN ROAD,HANGZHOU,CHINA
Hubei Lingsheng Pharmaceuticals Co., Ltd.

Contact:+86-0710-3538058

Address:Xiangyang City Xiangcheng Economic Development Zone, Hubei Province
Jinhua Haoyuan Chemical CO., LTD(expird)

Contact:86-579-82465583

Address:Jinhua,Zhejiang

Relevant to this article

An efficient synthesis of 2-Alkylthio-5-phenylmethylidene-4H-imidazolin-4-ones

Doi:10.1081/SCC-120018686
(2003)
Doi:10.1021/jo01035a515
(1964)
An efficient synthesis of oxetanones from α,β-epoxy diazomethyl ketones

Doi:10.1016/S0040-4020(01)92288-4
(1992)
Doi:10.1063/1.442485
(1981)
Selective cytotoxicity of oxysterols through structural modulation on rings A and B. Synthesis, in vitro evaluation, and SAR

Doi:10.1021/jm200803d
(2011)
Reductive and Catalytic Rearrangements of 2-Vinyl-1,3-Thiazetidines

Doi:10.1016/S0040-4020(01)89044-X
(1992)

Article Doi