Calcium entry blockers and activators: Conformational and structural determinants of dihydropyrimidine calcium channel modulators

DOI: 10.1021/jm00001a017

Source and publish data:

Journal of Medicinal Chemistry p. 119 - 129 (1995)

Update date:2022-08-05

Topics:

Authors:

Rovnyak Rovnyak

Kimball Kimball

Beyer Beyer

Cucinotta

DiMarco DiMarco

Gougoutas

Hedberg Hedberg

Malley Malley

McCarthy

Zhang Zhang

Moreland

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Article abstract of DOI:10.1021/jm00001a017

Dihydropyrimidines 4, 6, and 15, uniquely designed to unambiguously establish structural and conformational determinants for DHP receptor occupation and for modulation of calcium channel function, were prepared and examined for calcium channel modulation.

Full text of DOI:10.1021/jm00001a017

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