1,3-Dioxolanylpurine nucleosides (2R,4R) and (2R,4S) with selective anti- HIV-1 activity in human lymphocytes

DOI: 10.1021/jm00053a004

Source and publish data:

Journal of Medicinal Chemistry p. 30 - 37 (1993)

Update date:2022-08-04

Topics:

Authors:

Kim Kim

Schinazi

Nampalli

Shanmuganathan

Cannon Cannon

Alves Alves

Jeong Jeong

Beach Beach

Chu Chu

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Article abstract of DOI:10.1021/jm00053a004

In order to study the structure-activity relationships of dioxolane nucleosides as potential anti-HIV-1 agents, various enantiomers of pure dioxolanylpurine nucleosides were synthesized and evaluated against HIV-1 in human peripheral blood mononuclear cel

Full text of DOI:10.1021/jm00053a004

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Product name:1,3-Dioxolane-2-methanol, 4-(2-amino-6-chloro-9H-purin-9-yl)-, (2R,4R)-

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