Palladium Catalysed Synthesis of Spiroindolines.

Article abstract of DOI:10.1016/S0040-4020(01)80760-2

A series of palladium catalysed consecutive bis(5-exo trig)-, 5-exo trig-6-exo trig-, and 5-exo trig-7-endo trig-cyclisations via an alkene relay onto benzene or a wide range of heterocycles (pyrrole, furan, thiophen, indole, pyridine, pyridones) generates 5,5-, 5,6- and 5,7-spiroindolines in good yield.