Palladium Catalysed Synthesis of Spiroindolines.

DOI: 10.1016/S0040-4020(01)80760-2

Source and publish data:

Tetrahedron p. 359 - 370 (1994)

Update date:2022-08-04

Topics:

Authors:

Grigg, Ronald

Fretwell, Paul

Meerholtz, Clive

Sridharan, Visuvanathar

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Article abstract of DOI:10.1016/S0040-4020(01)80760-2

A series of palladium catalysed consecutive bis(5-exo trig)-, 5-exo trig-6-exo trig-, and 5-exo trig-7-endo trig-cyclisations via an alkene relay onto benzene or a wide range of heterocycles (pyrrole, furan, thiophen, indole, pyridine, pyridones) generates 5,5-, 5,6- and 5,7-spiroindolines in good yield.

Full text of DOI:10.1016/S0040-4020(01)80760-2

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