Synthesis and Biological Actions of Optically Active Enediynes Related to Dynemicin A

DOI: 10.1039/c39920001542

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 1542 - 1544 (1992)

Update date:2022-09-26

Topics:

Authors:

Nicolaou, K. C.

Hong, Y. P.

Dai, W.-M.

Zeng, Z.-J.

Wrasidlo, W.

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Article abstract of DOI:10.1039/c39920001542

Enantiomerically pure enediynes (+)-2 and (-)-2 were synthesized using a chiral resolution method and were shown to exhibit different cytotoxicities against a number of tumour cells.

Full text of DOI:10.1039/c39920001542

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