Synthesis of a Novel Pyrrolopyrimidine Alkaloid, Rigidin

DOI: 10.1021/jo00054a024

Source and publish data:

Journal of Organic Chemistry p. 403 - 407 (1993)

Update date:2022-08-03

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Authors:

Edstrom, Eric D.

Wei, Yuan

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Article abstract of DOI:10.1021/jo00054a024

An efficient nine-step synthesis of the brain phosphodiesterase inhibitor, rigidin, has been accomplished in 26percent overall yield starting from 6-chlorouracil and ethyl (2,4-dimethoxybenzyl)glycinate.A key feature of the synthetic route reveals a new m

Full text of DOI:10.1021/jo00054a024

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