Bioorganic and Medicinal Chemistry Letters p. 193 - 198 (1997)
Update date:2022-08-03
Topics:
Miller, Andrew
Askew, Marion
Beckett, R. Paul
Bellamy, Claire L.
Bone, Elisabeth A.
Coates, Rachael E.
Davidson, Alan H.
Drummond, Alan H.
Huxley, Philip
Martin, Fionna M.
Saroglou, Lydia
Thompson, Alison J.
Van Dijk, Sonja E.
Whittaker, Mark
Peptidomimetic carboxylate- and hydroxamate-based inhibitors of matrix metalloproteinases containing extended P1' groups have been prepared. Potent inhibition and good selectivity for MMP-2 has been observed for the compounds produced.
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