
Journal of Organic Chemistry p. 678 - 682 (1993)
Update date:2022-09-26
Topics:
Herrinton, Paul M.
Klotz, Karen L.
Hartley, William M.
Trospectomycin can be prepared in five steps from spectinomycin.The overall yield of the process is 13.3 percent.The synthesis involves a new oxidation of silyl enol ether 4 to enone 5 by use of an alkyl hydroperoxide.This reaction is mild and very selcti
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