Synthesis and cytotoxic evaluation of some 6-arylidene-2-(α- hydroxyamino-α-arylmethyl)cyclohexanone oximes and related compounds

Article abstract of DOI:10.1002/jps.2600811103

Reaction of 2,6-bis-(phenylmethylene)cyclohexanone (1) with a 4-molar excess of hydroxylamine hydrochloride and sodium acetate to produce the corresponding oxime 2 gave rise to 2-(α-hydroxyamino-α-phenylmethyl)-6- phenylmethylenecyclohexanone oxime (5a),