A New Efficient Synthesis of the Biologically Potent PGD2-Analogue ZK118182

DOI: 10.1016/S0957-4166(00)86051-6

Source and publish data:

Tetrahedron Asymmetry p. 1525 - 1528 (1992)

Update date:2022-07-30

Topics:

Authors:

Okamoto, Sentaro

Katayama, Satoshi

Ono, Naoya

Sato, Fumie

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0957-4166(00)86051-6

A highly stereoselective and practical synthetic method for ZK118182, which is chemically and metabolically stable and a biologically potent PGD₂-analogue developed by Schering AG, is reported.

Full text of DOI:10.1016/S0957-4166(00)86051-6

Products guided by the article

Product name:(1S,2R,3R,4R)-4-(tert-Butyl-dimethyl-silanyloxy)-3-[(E)-(S)-3-(tert-butyl-dimethyl-silanyloxy)-3-cyclohexyl-propenyl]-2-((Z)-4-hydroxy-but-2-enyl)-cyclopentanol

Cas No:146382-63-0

R&D Labs maybe for 146382-63-0

Zhejiang Tianyu Pharmaceutical Co., Ltd.

Contact:+86-576-84177669, 89189665,89189688,84168770

Address:Jiangkou Development Zone, Huangyan, Taizhou City, Zhejiang
JIANGXI AIFEIMU TECHNOLOGY CO.，LTD

Contact:+86-570-6040289

Address:FINECHEMICAL PARK,ZIBU TOWN,WANNIAN COUNTY,JIANGXI PROV.,CHINA,ZIP
Hubei Vanz Pharm Co.,Ltd

website:http://www.vanzpharm.com/en/index.html

Contact:86-27-84492310

Address:FANHU INDUSTRY PARK
Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

website:http://www.jlpharms.com

Contact:86-571-86982636

Address:Rm A606, Fuyi Center, jianqiao street
Liaoning Yufeng Chemical Co.,Ltd.

Contact:86-0419-3418888

Address:The metallurgical industrial zone,shoushan town, Liaoyang, Liaoning, China

Relevant to this article

Solid-phase synthesis of isoxazole-based amino acids: A new scaffold for molecular diversity

Doi:10.1021/jo015758v
(2001)
A magnetic nanoparticle-supported sulfuric acid as a highly efficient and reusable catalyst for rapid synthesis of amidoalkyl naphthols

Doi:10.1016/j.molcata.2013.08.028
(2013)
Electron-Transfer Photooxygenation. 5. Oxidation of Phenyl-Substituted Alkenes Sensitized by Cyanoanthracenes

Doi:10.1021/ja00539a018
(1980)
Redox-Neutral Synthesis of Selenoesters by Oxyarylation of Selenoalkynes under Mild Conditions

Doi:10.1021/acs.orglett.8b02544
(2018)
Two- and Four-Carbon Homologation of Aldehyde by AgClO4-Catalyzed Addition of Alkoxyalkenylzirconocene Chloride

Doi:10.1016/S0040-4039(00)60583-X
(1993)
Synthesis of (R)-(+)-patulolide A

Doi:10.1055/s-1993-25820
(1993)

Article Doi