Synthesis and Selective Cleavage of an Oligodeoxynucleotide Containing a Bridged Non-Chiral Internucleotide 3'-Phosphoramidate Linkage

DOI: 10.1016/S0040-4039(00)60176-4

Source and publish data:

Tetrahedron Letters p. 7319 - 7323 (1992)

Update date:2022-08-04

Topics:

Authors:

Mag, Matthias

Schmidt, Rainer

Engels, Joachim W.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)60176-4

A self complementary oligodeoxynucleotide dodecamer containing an achiral bridged 3'-phosphoramidate linkage 3'-NH-P-O-5' has been prepared using the solid phase phosphoramidate procedure.Cleavage of the P-N bond can be accomplished selectively by mild acidolysis.

Full text of DOI:10.1016/S0040-4039(00)60176-4

Products guided by the article

Product name:Phosphorous acid (2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-3-(tert-butyl-dimethyl-silanyloxy)-tetrahydro-furan-2-ylmethyl ester dimethyl ester

Cas No:146578-13-4

R&D Labs maybe for 146578-13-4

XI'AN CHUKANG BIOTECHNOLOGY CO.,LTD

Contact:29-63685658 63685359

Address:Room 3-1202,Building 1,Oriental oasis,East of Xianning Road,Xi'an,Shaanxi 710043 P.R.China
Jiangsu Taihu New Materials Holding Co., Ltd

Contact:+86-519-86160108

Address:Xueyan Town, Changzhou City, Jiangsu Province, 213169, China
Fujian Huitian Biological Pharmacy Co., Ltd.

Contact:0086-598-8300831; 8339920

Address:No.46,Taijiang Road,Sanming City,Fujian,China
Oren Hydrocarbons (Qingdao) Co., Ltd.

Contact:+86-532-68607667-801

Address:Room 3 # 302, No.9 Qingyun Road, Qingdao, China
Nowa pharmaceuticals Co., LTD

Contact:86-512-69362780,69362785

Address:No.69 Weixin Road,Weiting Town,Suzhou Industrial Park

Relevant to this article

Discovery of novel N-substituted carbazoles as neuroprotective agents with potent anti-oxidative activity

Doi:10.1016/j.ejmech.2013.07.029
(2013)
Heteroadamantanes and their Derivatives. 15. Synthesis of Derivatives of 9-Amino-3,6-diazahomoadamantanes

Doi:10.1007/BF00475253
(1992)
Enantiopure DAVA-Derivatives-Part III. Synthesis of All 4 Stereoisomers of 2-Methyl-4-hydroxy-5-aminopentanoic Acid (2-Me-4-OH-DAVA)

Doi:10.1016/S0957-4166(00)86022-X
(1993)
Photochemical Reaction of Phthalimides and Dicyanophthalimides with Benzylic Donors

Doi:10.1021/jo00059a023
(1993)
Palladium nanoparticles supported on agarose-catalyzed Heck-Matsuda and Suzuki-Miyaura coupling reactions using aryl diazonium salts

Doi:10.1002/aoc.2932
(2013)
Synthesis of new potent and selective aromatase inhibitors based on long-chained diarylalkylimidazole and diarylalkyltriazole molecule skeletons

Doi:10.1016/S0928-0987(00)00074-9
(2000)

Article Doi