Synthesis and Selective Cleavage of an Oligodeoxynucleotide Containing a Bridged Non-Chiral Internucleotide 3'-Phosphoramidate Linkage

DOI: 10.1016/S0040-4039(00)60176-4

Source and publish data:

Tetrahedron Letters p. 7319 - 7323 (1992)

Update date:2022-08-04

Topics:

Authors:

Mag, Matthias

Schmidt, Rainer

Engels, Joachim W.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)60176-4

A self complementary oligodeoxynucleotide dodecamer containing an achiral bridged 3'-phosphoramidate linkage 3'-NH-P-O-5' has been prepared using the solid phase phosphoramidate procedure.Cleavage of the P-N bond can be accomplished selectively by mild acidolysis.

Full text of DOI:10.1016/S0040-4039(00)60176-4

Products guided by the article

Product name:Phosphorous acid (2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-3-(tert-butyl-dimethyl-silanyloxy)-tetrahydro-furan-2-ylmethyl ester dimethyl ester

Cas No:146578-13-4

R&D Labs maybe for 146578-13-4

Chemieliva Pharmaceutical Co., Ltd.

website:http://www.chemieliva.com

Contact:+86-23-67770219

Address:99 Longhua Road, Yubei District, 401147, Chongqing, China Email: sales@chemieliva.com Tel:0086-23-67770219 Fax: 0086-23-67770220 Attn: Andy Huang
Shandong Zhongcheng Barium Salt Co., Ltd

Contact:+86-15725732638

Address:No.29 baoxi road, hi-tech zone, zibo, shandong
VanderArk International Limited

Contact:86-10-82437576

Address:Qing He
Suzhou Time-chem Technologies Co., Ltd.

Contact:0512-63983931/68086856

Address:No. 1326 of Binhe Road, New District, Suzhou, Jiangsu, P. R. China
ABA Chemicals (Shanghai) Limited

Contact:021- 5115 9199-232

Address:Suite 18D, #201 Ningxia Road,

Relevant to this article

Discovery of novel N-substituted carbazoles as neuroprotective agents with potent anti-oxidative activity

Doi:10.1016/j.ejmech.2013.07.029
(2013)
Heteroadamantanes and their Derivatives. 15. Synthesis of Derivatives of 9-Amino-3,6-diazahomoadamantanes

Doi:10.1007/BF00475253
(1992)
Enantiopure DAVA-Derivatives-Part III. Synthesis of All 4 Stereoisomers of 2-Methyl-4-hydroxy-5-aminopentanoic Acid (2-Me-4-OH-DAVA)

Doi:10.1016/S0957-4166(00)86022-X
(1993)
Photochemical Reaction of Phthalimides and Dicyanophthalimides with Benzylic Donors

Doi:10.1021/jo00059a023
(1993)
Palladium nanoparticles supported on agarose-catalyzed Heck-Matsuda and Suzuki-Miyaura coupling reactions using aryl diazonium salts

Doi:10.1002/aoc.2932
(2013)
Synthesis of new potent and selective aromatase inhibitors based on long-chained diarylalkylimidazole and diarylalkyltriazole molecule skeletons

Doi:10.1016/S0928-0987(00)00074-9
(2000)

Article Doi