4-Hydroxy-2-quinolones. 4. Selection of the Optimum Path for the Synthesis of N-R-Substituted 4-Hydroxy-2-quinolone-3-carboxylic Acid Amides

DOI: 10.1007/BF00475252

Source and publish data:

Chemistry of Heterocyclic Compounds p. 538 - 540 (1992)

Update date:2022-07-29

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Authors:

Ukrainets, I. V.

Bezuglyi, P. A.

Treskach, V. I.

Turov, A. V.

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Article abstract of DOI:10.1007/BF00475252

A comparison of several methods of preparation of N-R-substituted 4-hydroxy-2-quinolone-3-carboxylic acid amides showed that intramolecular cyclization of 2-carbalkoxymalonanilic acid ethyl esters with simultaneous amidation is the most rational method.

Full text of DOI:10.1007/BF00475252

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