
Tetrahedron Letters p. 133 - 136 (1993)
Update date:2022-08-03
Topics:
Dolle, Roland E.
McNair, David
A novel series of guanine nucleoside analogues 5-8 which contain a C-terminal sulfoximine have been synthesized.Key features of the synthesis include 1) the successful application of the trifluoroacetyl functional group as a stable, base-labile protecting group for the sulfoximine nitrogen and 2) the Mitsunobu-type coupling of alcohols 14 and 18-20 with purine 15.
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Doi:10.1002/jps.2600560523
(1967)Doi:10.1055/s-1993-25783
(1993)Doi:10.1016/0022-328X(92)83391-T
(1992)Doi:10.1002/adsc.201200477
(2012)Doi:10.1021/ja00219a071
(1988)Doi:10.1021/jo01265a032
(1968)