Tetrahedron Letters p. 595 - 598 (1993)
Update date:2022-08-03
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Cycloaddition of N-trimethylsilylimines 3 with the lithiotosylmethylisocyanates 4 is described. This provides a novel synthesis of 4-substituted and 4,5-disubstituted imidazoles from easily accessible aldehydes or organolithium reagents, under mild conditions and in a one-pot operation.
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Doi:10.1038/162746a0
(1948)Doi:10.1055/s-1991-26584
(1991)Doi:10.1021/ja01153a077
(1951)Doi:10.1016/S0040-4020(01)80329-X
(1993)Doi:10.1021/jo050131o
(2005)Doi:10.1039/c9ob01422e
(2019)
