Tetrahedron p. 863 - 880 (1993)
Update date:2022-08-03
Topics:
Toth, Gabor
Levai, Albert
Szoellosy, Aron
Duddeck, Helmut
A series of spiropyrazolines has been synthesized by 1,3-dipolar cycloaddition of E- and Z-3-arylidene-chromanones, -1-thiochromanones, -flavanones, -1-thioflavanones as well as 2-benzylidene-1-indanone, -1-benzosuberone with diazomethane. It has been found that this cycloaddition is regio- and stereoselective affording trans- and cis- spiro-1-pyrazolines. Spiro-1-pyrazolines were converted into spiro-2-pyrazolines on acid-catalysed isomerization. Conformation and relative configuration of compounds prepared has been elucidated by various one- and two-dimensional n.m.r. methods.
View MoreContact:+86-570-4336358
Address:No.87 Building,Tianqian,Sidu Town
Contact:+86-025-52406782
Address:8 Taizishan Rd., Yanjiang Industrial Development Area, Nanjing, Jiangsu, China.
Hefei EnliPharma Tecnology Co.,Ltd
Contact:0086-551-66399836
Address:Qing Cheng ShuiXiang Building 805, Mengcheng North Road , ShuangFeng Economic Development Zone Anhui HeFei
PINGYUAN SIHUAN PHARMACEUTICAL CO., LTD
Contact:+86-531-55696072
Address:#2766,yinxiu Road, Economic Development Zone, Pingyuan Country, Shandong Province, China.
Zhejiang Tianyu Pharmaceutical Co., Ltd.
Contact:+86-576-84177669, 89189665,89189688,84168770
Address:Jiangkou Development Zone, Huangyan, Taizhou City, Zhejiang
Doi:10.1039/DT9930003373
(1993)Doi:10.1021/jo000719p
(2000)Doi:10.1016/S0040-4020(01)80349-5
(1993)Doi:10.1021/jm400485e
(2013)Doi:10.1246/cl.1993.287
(1993)Doi:10.1021/ja00060a006
(1993)
