Regioselective metalation of ortho-aminopicolines using the pivaloyl group as a directing group: Synthesis of naphthyridines

Article abstract of DOI:10.1080/00397919308009790

2-(1,3-Dioxan-2-yl)-3-methyl-4- and 2-chloro-3,4-dimethyl-5-pivaloylaminopyridines were prepared and converted to 1,6- and 1,7-naphthylpyridines via regioselective lithiation of the ortho-methyl group, reaction with 2,2-diethoxyacetophenone and subsequent

Full text of DOI:10.1080/00397919308009790

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Synthetic Communications: An
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Organic Chemistry
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Regioselective Metalation
of Ortho-Aminopicolines
Using the Pivaloyl Group as a
Directing Group: Synthesis of
Naphthyridines
Alexander Straub a
a Bayer AG, Pharma Research Center, Chemical
Science Laboratories , POB 101709, W-5600,
Wuppertal, 1
Published online: 23 Sep 2006.
To cite this article: Alexander Straub (1993) Regioselective Metalation of
Ortho-Aminopicolines Using the Pivaloyl Group as a Directing Group: Synthesis
of Naphthyridines, Synthetic Communications: An International Journal for
Rapid Communication of Synthetic Organic Chemistry, 23:3, 365-372, DOI:
10.1080/00397919308009790
To link to this article: http://dx.doi.org/10.1080/00397919308009790
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