The synthesis of three indolizine derivatives of interest as non-isomerizable analogues of tamoxifen

DOI: 10.1002/jhet.5570320203

Source and publish data:

Journal of Heterocyclic Chemistry p. 391 - 394 (1995)

Update date:2022-09-26

Topics:

Authors:

Mehta Mehta

Parrick Parrick

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Article abstract of DOI:10.1002/jhet.5570320203

Three novel derivatives of indolizine 21, 23, and 25 have been prepared as analogues of the anti-cancer agent tamoxifen 1. The compounds showed low relative binding affinity at the estrogen receptor.

Full text of DOI:10.1002/jhet.5570320203

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