Tetrahedron Letters p. 1529 - 1532 (1993)
Update date:2022-08-04
Topics:
Appleton, Julie E.
Dack, Kevin N.
Green, Andrew D.
Steele, John
In the presence of triethylsilane and trifluoroacetic acid, the reaction between indoles and aldehydes in dichloromethane at 0 deg C, results in good yields of C-3 reductively alkylated products.The transformation is most effective for the preparation of 3-(arylmethyl)indoles 6 from aromatic aldehydes.
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Doi:10.1021/acs.joc.5b00851
(2015)Doi:10.1055/s-1993-25836
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(1994)Doi:10.1016/j.bmc.2018.10.016
(2018)Doi:10.1016/S0040-4039(00)77601-5
(1993)