Tetrahedron Letters p. 1529 - 1532 (1993)
Update date:2022-08-04
Topics:
Appleton, Julie E.
Dack, Kevin N.
Green, Andrew D.
Steele, John
In the presence of triethylsilane and trifluoroacetic acid, the reaction between indoles and aldehydes in dichloromethane at 0 deg C, results in good yields of C-3 reductively alkylated products.The transformation is most effective for the preparation of 3-(arylmethyl)indoles 6 from aromatic aldehydes.
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(2015)Doi:10.1055/s-1993-25836
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(1993)