Journal of the Chemical Society. Perkin Transactions 2 (2001) p. 1299 - 1304 (1996)
Update date:2022-09-26
Topics:
Abell, Andrew D.
Taylor, Jane M.
Oldham, Mark D.
The alkylation of (2R,4S)-3-benzoyl-4-benzyl-2-phenyloxazolidin-5-one 7 with diphenylmethyl bromoacetate proceeded with high diastereoselectivity, and the resulting product was hydrolysed to give [(2′R,4′5)-3′-benzoyl-4′-benzyl-5′-oxo-2′- phenyloxazolidin-4′-yl]acetic acid 9. The self-addition by-product (2R,45,1′S)-3-benzoyl-4-[benzoylamino(phenyl)methyl]-4-benzyl-2-phenyl-1, 3-oxazolidin-5-one 11 was also isolated. The structures of compound of 11 and the related self-addition products (2R,4S,1′S and 1′R)-3-benzoyl-4-[benzoylamino(phenyl)methyl]-4-isopropyl-2-phenyl-1,3- oxazolidin-5-one 20 and 21 were determined by X-ray crystallography. The mechanism of formation of the self-addition products is discussed.
View MoreContact:86-791-86629460
Address:1-6F, 118 Xinzhou road, Nanchang, Jiangxi, China
Zhengzhou Yuanli Biological Technology Co., Ltd.
Contact:+86-371-67897870/67897895
Address:No. 38, Qingyang Street, Zhengzhou, Henan, China
Shanghai Sunwise Chemical Co., Ltd
website:http://www.sunwisechem.com
Contact:86-021-33883180
Address:Room 10E, Building G, Westlink Center, No. 2337 Gudai Road, Minhang District, Shanghai, China PC: 201100
Contact:+86-10-62651721
Address:29 Yongxing Road, Daxing District,Beijing China
SHIJIAZHUANG HENRYTE CHEMICALS CO,.LTD(expird)
Contact:+86-311-85208698 311-80837698
Address:NO.166, yuhua west road, SHIJIAZHUANG, China
Doi:10.1016/j.ejmech.2013.09.030
(2013)Doi:10.1139/v72-445
(1972)Doi:10.1016/S0040-4039(00)60336-2
(1993)Doi:10.1016/j.molstruc.2013.07.015
(2013)Doi:10.1021/jo01234a004
(1936)Doi:10.1021/ol403096g
(2013)
