Synthetic study of marine macrolide swinholide A. Stereocontrolled synthesis of the c11-c32 segment

DOI: 10.1248/cpb.42.2403

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 2403 - 2405 (1994)

Update date:2022-08-03

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Authors:

Nakata Nakata

Komatsu Komatsu

Nagasawa

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Article abstract of DOI:10.1248/cpb.42.2403

The C24-C32 segment 4 of swinholide A (1) was stereoselectively synthesized starting from (S)-methyl 3-hydroxybutyrate, and the convergent synthesis of the C11-C32 segment 5 was accomplished via stereoselective aldol condensation of 3 and 4.

Full text of DOI:10.1248/cpb.42.2403

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