Towards the synthesis of streptovaricin D: Synthesis of fully elaborated aromatic precursors and coupling with ansa chain fragments

DOI: 10.1016/0040-4039(93)85004-G

Source and publish data:

Tetrahedron Letters p. 1553 - 1556 (1993)

Update date:2022-08-04

Topics: Purification and characterization Final steps Cross-Coupling Reactions Optimization and Scale-Up

Authors:

Roush Roush

Madar Madar

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Article abstract of DOI:10.1016/0040-4039(93)85004-G

The highly functionalized streptovaricin-damavaricin D aromatic precursors 12 and 15 have been prepared and coupled with propionaldehyde or unsaturated aldehydes 16 and 18 via aryllithium intermediates to give 2, 3 and 19.

Full text of DOI:10.1016/0040-4039(93)85004-G

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