SYNTHESIS OF 3'SUBSTITUTED-2',3'-DIDEOXYNUCLEOSIDE ANALOGS AS POTENTIAL ANTI-AIDS DRUGS

DOI: 10.1016/S0040-4039(00)99623-0

Source and publish data:

Tetrahedron Letters p. 1955 - 1958 (1989)

Update date:2022-08-04

Topics:

Authors:

Maillard, Michel

Faraj, Abdesslem

Frappier, Francois

Florent, Jean-Claude

Grierson, David S.

Monneret, Claude

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Article abstract of DOI:10.1016/S0040-4039(00)99623-0

3'-Amino-3'-deoxythymidine 9 was prepared in six steps and in 67percent overall yield from thymidine.Five derivatives of 9 and compound 17 were tested for their anti-HIV activity.

Full text of DOI:10.1016/S0040-4039(00)99623-0

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