Chemical and Pharmaceutical Bulletin p. 3094 - 3096 (1991)
Update date:2022-08-04
Topics: Synthesis Enantiomerically pure Derivatives Enantiomeric purity Facile Route Chemoenzymatic
Akita
Umezawa
Takano
Matsukura
Oishi
The reaction of 4,5-epoxy-2-hexenoate 2 and various nucleophiles in the presence of BF3.Et2O predominantly gave the (4,5)-5-hydroxy-4-substituted compounds. Among them, (±)-(4,5)-anti-5-hydroxy-4-thiophenoxy ester 17 was enantioselec
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(2021)
