Tetrahedron Letters p. 2437 - 2440 (1993)
Update date:2022-08-03
Topics:
Brandao, Marcos A. F.
Oliveira, Alaide Braga de
Snieckus, Victor
A general combined metalation-cross coupling methodology (Scheme 1) for the regiospecific construction of heteroring fused o-naphthoquinones 8 is described and its application to a short synthesis of the antimalarial/antitumor natural product β-lapachone (14) is demonstrated.
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