Collection of Czechoslovak Chemical Communications p. 575 - 587 (1993)
Update date:2022-08-04
Topics:
Kutschy, Peter
Dzurilla, Milan
Ficeri, Vlastimir
Koscik, Dusan
S-Allyl N-acylmonothiocarbamates react in boiling benzene with primary and secondary amines in the presence of catalytic amounts of triethylamine.In this reaction, the S-allyl group is replaced with the amino group under formation of N-acylurea derivatives in 45-90percent yields.The wide applicability of the reaction is demonstrated by the synthesis of eighty four N-acyl-N'-substituted and N-acyl-N',N'-disubstituted ureas with various aliphatic, aromatic and heterocyclic substituents.
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Doi:10.1016/0008-6215(93)80030-I
(1993)Doi:10.1021/jo01149a024
(1950)Doi:10.1016/j.jsbmb.2013.01.016
(2013)Doi:10.1055/s-2006-944187
(2006)Doi:10.1021/jo00067a010
(1993)Doi:10.1248/cpb.41.507
(1993)
