Tetrahedron Letters p. 6021 - 6024 (1991)
Update date:2022-08-05
Topics:
Dreef
Schiebler
Van der Marel
Van Boom
The racemic 5-phosphonate analogues IV and V of myo-inositol 1,4,5-trisphosphate were readily accessible by bisphosphorylation of the common precursor 6, removal of the p-methoxybenzyl group, phosphonylation and subsequent hydrogenolysis of the benzyl protecting groups. The methylphosphonate analogue IV acted as a calcium antagonist in permeabilized human platelets, whereas the (difluoromethyl)phosphonate V exhibited only very little antagonistic activity.
View MoreContact:+86-574-89075960
Address:#100 Xiang Yun Road, New High tech area, Ningbo, China
Reliable Pharmatech (Tianjin) Co., Ltd.
Contact:86-22-28567687
Address:Zuoanmingdi, Xianshuigu, Jinnan District
Shanghai Balmxy Pharmaceutical Co., Ltd
Contact:0086-21-24206007
Address:Room 402, 15#, No. 909 wangyue Road, shanghai, P. R. China
Tengzhou Runlong Fragrance Co., Ltd.
website:http://www.tzrunlong.com/
Contact:--
Address:No. 78, Fushan Road, Biomedical Industrial Park, Dawu Town, Tengzhou, Shandong, 277514 China
Contact:+86-28-88523492
Address:714rooms of Time Square, Pujiang County
Doi:10.1111/j.1545-5300.2002.41316.x
()Doi:10.1021/om400899g
(2013)Doi:10.1007/s11172-014-0438-5
(2014)Doi:10.1039/j39660002349
(1966)Doi:10.1016/j.bmc.2004.03.037
(2004)Doi:10.1021/jacs.6b01078
(2016)
