European Journal of Medicinal Chemistry p. 3 - 12 (1993)
Update date:2022-09-26
Topics:
Ho, W
Hageman, W E
Stanley, K G
Gallant, W R
Cherry, D A
et al.
A series of 6-hydroxy-7-thioether and 6-thioether-7-hydroxy derivatives of commercially available petroselinic acid and 5-hydroxy-6-thioether derivatives of fatty acids containing an aromatic moiety were synthesized.Several of the compounds have exhibited SRS-A antagonist (eg, 5, 10)/agonist (eg, 34, 35) activity.Compound 5 antagonized SRS-A-induced contractions of the isolated guinea pig ileum with IC50 = 0.09 μM. hydroxythioether fatty acids / SRS-A / antagonist / agonist / peptidoleukotriene analogs
View MoreContact:86-512-69362780,69362785
Address:No.69 Weixin Road,Weiting Town,Suzhou Industrial Park
Shandong Loyal Chemical industrial Co.,Ltd
Contact:0533-7451788
Address:Linzi Chemical Industrial Park, Zibo, Shandong Province
Shanghai Kangxin Chemical Co., Ltd
Contact:+86 21 60717227
Address:118,Ganbai Village,Waigang Town,Jiading District,Shanghai
Jinzhou Jiutai Pharmaceutical Co.,Ltd
Contact:+86-0416-5179890
Address:No.41, Taianli, Taihe District, Jinzhou, Liaoning
Shijiazhuang Haotian Chemical Co., Ltd.
Contact:86-311-85044374
Address:293 Donggang Road
Doi:10.1248/cpb.43.829
(1995)Doi:10.1016/0008-6215(93)84062-B
(1993)Doi:10.1002/chem.201705708
(2018)Doi:10.1002/psc.2771
(2015)Doi:10.1016/j.tetlet.2007.08.096
(2007)Doi:10.1002/recl.19931120502
(1993)
