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Total synthesis of (+)-goniodiol

DOI: 10.1016/0040-4039(95)02125-6

Source and publish data:

Tetrahedron Letters p. 371 - 374 (1996)

Update date:2022-07-29

Topics: Characterization   Total synthesis   Cytotoxicity   Carbon-carbon bond formation   Retrosynthetic analysis   Scale-up   Stereochemistry Control   Ring Formation   Protection and Functional Group Manipulation   Oxidation and reduction reactions  

Authors:

Surivet, Jean-PhilippeSurivet, Jean-Philippe

Gore, JacquesGore, Jacques

Vatele, Jean-MichaelVatele, Jean-Michael

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Article abstract of DOI:10.1016/0040-4039(95)02125-6

Cytotoxic styryl lactone, (+)-goniodiol 1, was prepared in enantioenriched form (33 92%) in 15 steps from the α-(α'-alkoxyallenic) alcohol 5.

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Full text of DOI:10.1016/0040-4039(95)02125-6

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Product name:(R)-2-[(3aR,5R,6S,6aR)-5-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yloxy]-1-phenyl-buta-2,3-dien-1-ol

Cas No:149180-78-9

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