The Reaction of Nitrones with (R)-(+)-Methyl p-Tolyl Sulfoxide Anion; Asymmetric Synthesis of Optically Active Secondary Amines

Article abstract of DOI:10.1016/S0040-4039(00)77646-5

Optically active α-substituted N-hydroxylamines have been prepared by the addition of (R)-(+)- and (S)-(-)-methyl p-tolyl sulfoxide anions of nitrones highly efficiently.This method is applicable to the synthesis of optically active N-hydroxy tetrahydrois