
Journal of Medicinal Chemistry p. 2075 - 2083 (1993)
Update date:2022-08-05
Topics:
Naylor
Judd
Lloyd
Scopes
Hayes
Birch
The synthesis of 4-substituted 1-(arylacetyl)-2- [(alkylamino)methyl]piperazines (10-22, 26, 27, and 30-33) and their activities as κ-opioid receptor agonists are described. This includes a range of 4-acyl and 4-carboalkoxy derivatives with the latter ser
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Doi:10.1039/DT9930000967
(1993)Doi:10.1021/jm00024a009
(1995)Doi:10.1021/ja01059a061
(1964)Doi:10.1021/ol403288n
(2014)Doi:10.1248/cpb.48.1129
(2000)Doi:10.1021/ol403209k
(2014)