A potent new class of κ-receptor agonist: 4-Substituted 1-(arylacetyl)- 2-[(dialkylamino)methyl]piperazines

DOI: 10.1021/jm00067a004

Source and publish data:

Journal of Medicinal Chemistry p. 2075 - 2083 (1993)

Update date:2022-08-05

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Authors:

Naylor Naylor

Judd Judd

Lloyd Lloyd

Scopes Scopes

Hayes Hayes

Birch Birch

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Article abstract of DOI:10.1021/jm00067a004

The synthesis of 4-substituted 1-(arylacetyl)-2- [(alkylamino)methyl]piperazines (10-22, 26, 27, and 30-33) and their activities as κ-opioid receptor agonists are described. This includes a range of 4-acyl and 4-carboalkoxy derivatives with the latter ser

Full text of DOI:10.1021/jm00067a004

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