Synthesis of nitroimidazole substituted 3,3,9,9-tetramethyl-4,8-diazaundecane-2,10-dione dioximes (propylene amine oximes, PnAOs): Ligands for technetium-99m complexes with potential for imaging hypoxic tissue

DOI: 10.1016/0040-4020(95)00042-7

Source and publish data:

Tetrahedron p. 2875 - 2894 (1995)

Update date:2022-08-03

Topics:

Authors:

Ramalingam, Kondareddiar

Raju, Natarajan

Nanjappan, Palaniappa

Nowotnik, David P.

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Article abstract of DOI:10.1016/0040-4020(95)00042-7

A series of 2-substituted-1,3-diaminopropanes (1b-1f, 1h) have been synthesized as precursors to nitroimidazole-substituted 3,3,9,9-tetramethyl-4,8-diazaundecane-2,10-dione dioxime (21b, 21d, 21e and 26a-26c) (Propylene Amine Oxime, PnAO) ligands. 3-Chlor

Full text of DOI:10.1016/0040-4020(95)00042-7

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