Tetrahedron p. 17029 - 17038 (1997)
Update date:2022-09-26
Topics:
Kitahara, Yoshiyasu
Nakahara, Shinsuke
Yonezawa, Takanobu
Nagatsu, Masanori
Shibano, Yoshikazu
Kubo, Akinori
A pentacyclic aromatic alkaloid, kuanoniamine A (6) was synthesized in three steps from 6-methoxybenzothiazole-4,7-dione (8) and 2-aminoacetophenone (9). 11-Hydroxyascididemin (4) was prepared from 5,8-quinolinedione (13, 14) or 1,4-acridinedione (20). The structure of neocalliactine acetate, a derivative of calliactine, was determined to be 5 by total synthesis from 6-methoxy-5,8-quinolinedione (28) and 2-amino-5-methoxyacetophenone (29).
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