Synthesis and biological evaluation of cholecystokinin analogs in which the Asp-Phe-NH2 moiety has been replaced by a 3-amino-7-phenylheptanoic acid or a 3-amino-6-(phenyloxy)hexanoic acid

DOI: 10.1021/jm00072a024

Source and publish data:

Journal of Medicinal Chemistry p. 3021 - 3028 (1993)

Update date:2022-09-26

Topics:

Authors:

Amblard Amblard

Rodriguez

Lignon Lignon

Galas Galas

Bernad Bernad

Artis-Noel -

Hauad Hauad

Laur Laur

Califano

Aumelas Aumelas

Martinez

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Article abstract of DOI:10.1021/jm00072a024

Boc-Tyr(SO₃H)-Nle-Gly-Trp-Nle-Asp-2-phenylethyl ester (JMV180), an analog of the C-terminal octapeptide of cholecystokinin (CCK-8), shows interesting biological activities behaving as an agonist at the high-affinity CCK binding sites and as an

Full text of DOI:10.1021/jm00072a024

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