Chemoenzymatic synthesis of acetyl (R)-(+)- and (S)-(-)-cycloserine

DOI: 10.1016/S0957-4166(00)80156-1

Source and publish data:

Tetrahedron Asymmetry p. 1073 - 1080 (1993)

Update date:2022-08-04

Topics:

Authors:

De Amici

De Micheli

Cateni Cateni

Carrea Carrea

Ottolina

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Article abstract of DOI:10.1016/S0957-4166(00)80156-1

The two enantiomers of acetyl cycloserine 8, the immediate precursors of the chiral forms of cycloserine 1, were prepared in enantiomeric excess higher than 98% by means of lipase-catalyzed hydrolysis of 3-benzyloxy-4-hydroxy-Δ²-isoxazoline but

Full text of DOI:10.1016/S0957-4166(00)80156-1

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