The Addition of Metallo Enolates to Chiral 1-Acylpyridinium Salts. An Asymmetric Synthesis of (-)-Sedamine

DOI: 10.1021/jo00071a005

Source and publish data:

Journal of Organic Chemistry p. 5035 - 5036 (1993)

Update date:2022-08-04

Topics:

Authors:

Comins, Daniel L.

Hong, Hao

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00071a005

Synthetically useful 2-(2-oxoalkyl)-2,3-dihydro-4-pyridones are prepared in high diastereomeric excess by addition of ketone metallo enolates to chiral 1-acyl-4-methoxypyridinium salts.

Full text of DOI:10.1021/jo00071a005

Products guided by the article

Product name:(R)-4-Oxo-2-(2-oxo-pentyl)-5-triisopropylsilanyl-3,4-dihydro-2H-pyridine-1-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester

Cas No:150931-13-8

R&D Labs maybe for 150931-13-8

ZHEJIANG CHEMICAL INDUSTRY INSTITUTE TECHNOLOGY CO.,LTD(expird)

Contact:86-575-82730298

Address:shangyu
Suzhou ATL Chemical Co.,ltd

Contact:+86-0512-69209969

Address:Room 317,Lushan Road,Suzhou New District,Jiangsu Province,China.
ZHANGJIAGANG FREE TRADE ZONE YONG HAN INTERNATIONAL TRADING CO., LTD(expird)

Contact:86 512 57910558

Address:qianjin M road
Shandong Jincheng Zhonghua Bio-pharmaceutical Co.,Ltd

Contact:+86-533-5415882

Address:Zichuan Economic Development Zone,Zibo City,Shandong Province,China
XinChem Corporation

Contact:+86 21 34123252

Address:14, 4580 Dushi, Shanghai, China

Relevant to this article

Synthesis and preliminary in vitro biological activity of non-steroidal cytotoxic estrogens designed for the treatment of breast cancer

Doi:10.1139/v93-171
(1993)
Total synthesis of nephritogenic glycopeptide, nephritogenoside

Doi:10.1016/S0040-4039(00)74132-3
(1992)
A simple, efficient, regioselective and one-pot preparation of N-hydroxy- and N-O-protected hydroxyindoles via cycloaddition of nitrosoarenes with alkynes. Synthetic scope, applications and novel by-products

Doi:10.1016/j.tet.2013.10.072
(2013)
A direct synthesis of a bifunctional chelating agent for radiolabeling proteins

Doi:10.1016/S0040-4039(00)79202-1
(1993)
Highly selective oxidative cross-coupling of 2-naphthol derivatives with chiral copper(I)-bisoxazoline catalysts

Doi:10.1016/j.tetlet.2005.06.098
(2005)
OXIDATION OF 1-METHYLCYCLOBUTANOL BY Pb(IV) AND Mn(III) COMPOUNDS

Doi:10.1007/BF01150744
(1992)

Article Doi