The Addition of Metallo Enolates to Chiral 1-Acylpyridinium Salts. An Asymmetric Synthesis of (-)-Sedamine

DOI: 10.1021/jo00071a005

Source and publish data:

Journal of Organic Chemistry p. 5035 - 5036 (1993)

Update date:2022-08-04

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Authors:

Comins, Daniel L.

Hong, Hao

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Article abstract of DOI:10.1021/jo00071a005

Synthetically useful 2-(2-oxoalkyl)-2,3-dihydro-4-pyridones are prepared in high diastereomeric excess by addition of ketone metallo enolates to chiral 1-acyl-4-methoxypyridinium salts.

Full text of DOI:10.1021/jo00071a005

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