Tetrahedron Asymmetry p. 1519 - 1520 (1995)
Update date:2022-08-04
Topics:
Raju, S. Bhaskar
Chiou, Tzyy-Wen
Tai, Dar-Fu
Pharmaceutrically useful chloro alcohols, 3-chloro-1-phenyl-1-propanol (1), 1-chloro-3-(1-naphthyloxy)-2-propanol (2) and 4-chloro-1-(4-tert-butylphenyl)-1-butanol (3), are prepared in enantiomerically pure form by an efficient lipase PS catalyzed transesterification in heptane.The effect of organic solvent nature on enzyme activity was also studied.
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