
Journal of Organic Chemistry p. 426 - 427 (1992)
Update date:2022-08-05
Topics:
Allen, Sarah T.
Heintzelman, Geoffrey R.
Toone, Eric J.
KDPG aldolase, a representative member of the largest but as of yet unexplored group of aldolases which utilize pyruvate as the nucleophilic component in aldol condensation, accepts a number of unnatural aldehydes as electrophiles in stereospecific aldol condensation, providing access to highly and differentially functionalized α-keto acid products.
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