Asymmetric synthesis of both enantiomers of acyloxy methyl 3,3-difluorolactate

DOI: 10.1016/S0957-4166(00)80127-5

Source and publish data:

Tetrahedron Asymmetry p. 889 - 892 (1993)

Update date:2022-09-26

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Authors:

Murata Murata

Kitzume Kitzume

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Article abstract of DOI:10.1016/S0957-4166(00)80127-5

Both enantiomers of acyloxy methyl 3,3-difluorolactate are synthesized via enzymatic optical resolution of furanol and transformed into chiral α-hydroxy ketone and diol. The absolute configuration of these materials is determined.

Full text of DOI:10.1016/S0957-4166(00)80127-5

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Product name:(S)-(+)-methyl benzyloxy 3,3-difluorolactate

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