
Chemical and Pharmaceutical Bulletin p. 1188 - 1190 (1993)
Update date:2022-09-26
Topics:
Ohta
Kamata
Inagaki
Masuda
Yamamoto
Yamashita
Kawasaki
Several N,N-diethyl-2-acylmethylbenzamides (6) were prepared from N,N- diethyl-2-toluamides (4), and the ketoamides (6) were easily cyclized to the corresponding 3-substituted isocoumarins (8) by heating in acetic acid or xylene. This simple procedure was
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