Tetrahedron Letters p. 5747 - 5750 (1993)
Update date:2022-09-26
Topics:
Katoh, Tadashi
Kirihara, Masayuki
Nagata, Yuriko
Kobayashi, Yuko
Arai, Katsuko
et al.
The title total synthesis was accomplished by employing diastereoselective reduction of 1,3-disubstituted isoquinolines as a key step.The cytotoxicity of 10-decarboxyquinocarcin and its 7-cyano congeners were found to be 10-1000 times more potent than tho
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