A mechanistic study of 2-vinylbenzimidazole formation from 2-(2'- haloethyl)benzimidazoles. Synthesis of highly electron-rich vinylic compounds by general base and specific acid-general base catalysis

Article abstract of DOI:10.1021/jo00079a025

The mechanism of halide elimination from 2-(haloethyl)-1-methyl-4,7- dihydroxybenzimidazole was studied in aqueous buffer by means of a pH-rate profile, buffer dilution studies, and ¹³C scrambling. It was anticipated that a spiro-fused cyclopro