Structural modification of 5-aryl-2,3-dihydroimidazo[2,1-a]isoquinoline platelet activating factor receptor antagonists

DOI: 10.1021/jm00073a008

Source and publish data:

Journal of Medicinal Chemistry p. 3098 - 3102 (1993)

Update date:2022-07-29

Topics:

Authors:

Houlihan

Cheon Cheon

Parrino Parrino

Handley Handley

Larson Larson

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Article abstract of DOI:10.1021/jm00073a008

In an effort to determine the effect of modification of the imidazo[2,1- a]isoquinoline portion of the PAF-receptor antagonist SDZ 64-412 (1), several new analogs were prepared and evaluated in vitro and in vivo. One of these, 5-[4-[2-(3,4,5-trimethoxyphe

Full text of DOI:10.1021/jm00073a008

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Product name:2-Methyl-5-{4-[2-(3,4,5-trimethoxy-phenyl)-ethyl]-phenyl}-2,3,5,6-tetrahydro-imidazo[2,1-a]isoquinolin-5-ol

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