Total synthesis of the macrolide antitumor antibiotic lankacidin C

DOI: 10.1021/ja00136a025

Source and publish data:

Journal of the American Chemical Society p. 8258 - 8270 (1995)

Update date:2022-07-31

Topics:

Authors:

Kende, Andrew S.

Liu, Kun

Kaldor, István

Dorey, Gilbert

Koch, Kevin

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Article abstract of DOI:10.1021/ja00136a025

The first total synthesis of natural (-)-lankacidin C (1) has been achieved by a convergent, enantioselective sequence starting from D-arabinose and L-aspartic acid, proceeding through the tricyclic carbamate 15 as an advanced relay intermediate. Specific

Full text of DOI:10.1021/ja00136a025

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