14β-[(p-Nitrocinnamoyl)amino]morphinones, 14β-[(p- nitrocinnamoyl)amino]-7,8-dihydromorphinones, and their codeinone analogues: Synthesis and receptor activity

Article abstract of DOI:10.1021/jm00073a015

A series of 14β-[(nitrocinnamoyl)amino]codeinones and morphinones, some of which contain a 5β-methyl group, were prepared from 14β-aminocodeinones and 14β-[N-(cyclopropylmethyl)-amino]norcodeinones. The affinities of the target compounds for the μ, δ, and